Somatic Mutations in Renal Cyst Epithelium in Autosomal Dominant Polycystic Kidney Disease

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a ciliopathy caused by mutations in PKD1 and PKD2 that is characterized by renal tubular epithelial cell proliferation and progressive CKD. Although the molecular mechanisms involved in cystogenesis are not established, concurrent i...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Tan, Adrian Y., Zhang, Tuo, Michaeel, Alber, Blumenfeld, Jon, Liu, Genyan, Zhang, Wanying, Zhang, Zhengmao, Zhu, Yi, Rennert, Lior, Martin, Che, Xiang, Jenny, Salvatore, Steven P., Robinson, Brian D., Kapur, Sandip, Donahue, Stephanie, Bobb, Warren O., Rennert, Hanna
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2018
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065086/
https://ncbi.nlm.nih.gov/pubmed/30042192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017080878
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