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Somatic Mutations in Renal Cyst Epithelium in Autosomal Dominant Polycystic Kidney Disease
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a ciliopathy caused by mutations in PKD1 and PKD2 that is characterized by renal tubular epithelial cell proliferation and progressive CKD. Although the molecular mechanisms involved in cystogenesis are not established, concurrent i...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Am Soc Nephrol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society of Nephrology
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6065086/ https://ncbi.nlm.nih.gov/pubmed/30042192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017080878 |
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