Somatic Mutations in Renal Cyst Epithelium in Autosomal Dominant Polycystic Kidney Disease

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a ciliopathy caused by mutations in PKD1 and PKD2 that is characterized by renal tubular epithelial cell proliferation and progressive CKD. Although the molecular mechanisms involved in cystogenesis are not established, concurrent i...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Tan, Adrian Y., Zhang, Tuo, Michaeel, Alber, Blumenfeld, Jon, Liu, Genyan, Zhang, Wanying, Zhang, Zhengmao, Zhu, Yi, Rennert, Lior, Martin, Che, Xiang, Jenny, Salvatore, Steven P., Robinson, Brian D., Kapur, Sandip, Donahue, Stephanie, Bobb, Warren O., Rennert, Hanna
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2018
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065086/
https://ncbi.nlm.nih.gov/pubmed/30042192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017080878
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