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Macrophages Promote Cyst Growth in Polycystic Kidney Disease

Polycystic kidney disease (PKD) exhibits an inflammatory component, but the contribution of inflammation to cyst progression is unknown. Macrophages promote the proliferation of tubular cells following ischemic injury, suggesting that they may have a role in cystogenesis. Furthermore, cultured Pkd1-...

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Detalhes bibliográficos
Main Authors: Karihaloo, Anil, Koraishy, Farrukh, Huen, Sarah C., Lee, Yashang, Merrick, David, Caplan, Michael J., Somlo, Stefan, Cantley, Lloyd G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187181/
https://ncbi.nlm.nih.gov/pubmed/21921140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011010084
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