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miR-17∼92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease

Polycystic kidney disease (PKD), the most common genetic cause of chronic kidney failure, is characterized by the presence of numerous, progressively enlarging fluid-filled cysts in the renal parenchyma. The cysts arise from renal tubules and are lined by abnormally functioning and hyperproliferativ...

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Библиографические подробности
Главные авторы: Patel, Vishal, Williams, Darren, Hajarnis, Sachin, Hunter, Ryan, Pontoglio, Marco, Somlo, Stefan, Igarashi, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696812/
https://ncbi.nlm.nih.gov/pubmed/23759744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301693110
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