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miR-17∼92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease

Polycystic kidney disease (PKD), the most common genetic cause of chronic kidney failure, is characterized by the presence of numerous, progressively enlarging fluid-filled cysts in the renal parenchyma. The cysts arise from renal tubules and are lined by abnormally functioning and hyperproliferativ...

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Autori principali: Patel, Vishal, Williams, Darren, Hajarnis, Sachin, Hunter, Ryan, Pontoglio, Marco, Somlo, Stefan, Igarashi, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696812/
https://ncbi.nlm.nih.gov/pubmed/23759744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301693110
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