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miR-17∼92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease

Polycystic kidney disease (PKD), the most common genetic cause of chronic kidney failure, is characterized by the presence of numerous, progressively enlarging fluid-filled cysts in the renal parenchyma. The cysts arise from renal tubules and are lined by abnormally functioning and hyperproliferativ...

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Detalhes bibliográficos
Main Authors: Patel, Vishal, Williams, Darren, Hajarnis, Sachin, Hunter, Ryan, Pontoglio, Marco, Somlo, Stefan, Igarashi, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696812/
https://ncbi.nlm.nih.gov/pubmed/23759744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301693110
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