Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by renal cyst formation, inflammation, and fibrosis. Macrophages infiltrate cystic kidneys, but the role of these and other inflammatory factors in disease progression are poorly understood. Here, we identified macrophage migratio...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Chen, Li, Zhou, Xia, Fan, Lucy X., Yao, Ying, Swenson-Fields, Katherine I., Gadjeva, Mihaela, Wallace, Darren P., Peters, Dorien J.M., Yu, Alan, Grantham, Jared J., Li, Xiaogang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497763/
https://ncbi.nlm.nih.gov/pubmed/25961459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80467
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