Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by renal cyst formation, inflammation, and fibrosis. Macrophages infiltrate cystic kidneys, but the role of these and other inflammatory factors in disease progression are poorly understood. Here, we identified macrophage migratio...

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Publicat a:J Clin Invest
Autors principals: Chen, Li, Zhou, Xia, Fan, Lucy X., Yao, Ying, Swenson-Fields, Katherine I., Gadjeva, Mihaela, Wallace, Darren P., Peters, Dorien J.M., Yu, Alan, Grantham, Jared J., Li, Xiaogang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497763/
https://ncbi.nlm.nih.gov/pubmed/25961459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80467
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