Hepatitis A Virus Codon Usage: Implications for Translation Kinetics and Capsid Folding

Codon usage bias is universal to all genomes. Hepatitis A virus (HAV) codon usage is highly biased and deoptimized with respect to its host. Accordingly, HAV is unable to induce cellular translational shutoff and its internal ribosome entry site (IRES) is inefficient. Codon usage deoptimization may...

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Bibliografski detalji
Izdano u:Cold Spring Harb Perspect Med
Glavni autori: Pintó, Rosa M., Pérez-Rodríguez, Francisco-Javier, D’Andrea, Lucia, de Castellarnau, Montserrat, Guix, Susana, Bosch, Albert
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2018
Teme:
Perspectives
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169985/
https://ncbi.nlm.nih.gov/pubmed/29530949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a031781
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