Hepatitis A Virus Codon Usage: Implications for Translation Kinetics and Capsid Folding

Codon usage bias is universal to all genomes. Hepatitis A virus (HAV) codon usage is highly biased and deoptimized with respect to its host. Accordingly, HAV is unable to induce cellular translational shutoff and its internal ribosome entry site (IRES) is inefficient. Codon usage deoptimization may...

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Publicat a:Cold Spring Harb Perspect Med
Autors principals: Pintó, Rosa M., Pérez-Rodríguez, Francisco-Javier, D’Andrea, Lucia, de Castellarnau, Montserrat, Guix, Susana, Bosch, Albert
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2018
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Perspectives
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6169985/
https://ncbi.nlm.nih.gov/pubmed/29530949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a031781
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