Combined Systemic Disruption of MET and Epidermal Growth Factor Receptor Signaling Causes Liver Failure in Normal Mice

MET and epidermal growth factor receptor (EGFR) tyrosine kinases are crucial for liver regeneration and normal hepatocyte function. Recently, we demonstrated that in mice, combined inhibition of these two signaling pathways abolished liver regeneration after hepatectomy, with subsequent hepatic fail...

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Xehetasun bibliografikoak
Argitaratua izan da:Am J Pathol
Egile Nagusiak: Tsagianni, Anastasia, Mars, Wendy M., Bhushan, Bharat, Bowen, William C., Orr, Anne, Stoops, John, Paranjpe, Shirish, Tseng, George C., Liu, Silvia, Michalopoulos, George K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168971/
https://ncbi.nlm.nih.gov/pubmed/30031724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.06.009
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