Combined Systemic Disruption of MET and Epidermal Growth Factor Receptor Signaling Causes Liver Failure in Normal Mice

MET and epidermal growth factor receptor (EGFR) tyrosine kinases are crucial for liver regeneration and normal hepatocyte function. Recently, we demonstrated that in mice, combined inhibition of these two signaling pathways abolished liver regeneration after hepatectomy, with subsequent hepatic fail...

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Publicado en:Am J Pathol
Autores principales: Tsagianni, Anastasia, Mars, Wendy M., Bhushan, Bharat, Bowen, William C., Orr, Anne, Stoops, John, Paranjpe, Shirish, Tseng, George C., Liu, Silvia, Michalopoulos, George K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168971/
https://ncbi.nlm.nih.gov/pubmed/30031724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.06.009
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