Combined Systemic Disruption of MET and Epidermal Growth Factor Receptor Signaling Causes Liver Failure in Normal Mice

MET and epidermal growth factor receptor (EGFR) tyrosine kinases are crucial for liver regeneration and normal hepatocyte function. Recently, we demonstrated that in mice, combined inhibition of these two signaling pathways abolished liver regeneration after hepatectomy, with subsequent hepatic fail...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Tsagianni, Anastasia, Mars, Wendy M., Bhushan, Bharat, Bowen, William C., Orr, Anne, Stoops, John, Paranjpe, Shirish, Tseng, George C., Liu, Silvia, Michalopoulos, George K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168971/
https://ncbi.nlm.nih.gov/pubmed/30031724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.06.009
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