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Endothelium-specific amyloid precursor protein deficiency causes endothelial dysfunction in cerebral arteries

The exact physiological function of amyloid-β precursor protein (APP) in endothelial cells is unknown. Endothelium-specific APP-deficient (eAPP(−/−)) mice were created to gain new insights into the role of APP in the control of vascular endothelial function. Endothelium-dependent relaxations to acet...

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Dettagli Bibliografici
Pubblicato in:J Cereb Blood Flow Metab
Autori principali: d’Uscio, Livius V, He, Tongrong, Santhanam, Anantha V, Katusic, Zvonimir S
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168907/
https://ncbi.nlm.nih.gov/pubmed/28959912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17735418
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