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Role of prostacyclin signaling in endothelial production of soluble amyloid precursor protein-α in cerebral microvessels

We tested hypothesis that activation of the prostacyclin (PGI(2)) receptor (IP receptor) signaling pathway in cerebral microvessels plays an important role in the metabolism of amyloid precursor protein (APP). In human brain microvascular endothelial cells activation of IP receptor with the stable a...

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Dettagli Bibliografici
Pubblicato in:J Cereb Blood Flow Metab
Autori principali: He, Tongrong, Santhanam, Anantha Vijay R, Lu, Tong, d'Uscio, Livius V, Katusic, Zvonimir S
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363732/
https://ncbi.nlm.nih.gov/pubmed/26661245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X15618977
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