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Role of prostacyclin signaling in endothelial production of soluble amyloid precursor protein-α in cerebral microvessels

We tested hypothesis that activation of the prostacyclin (PGI(2)) receptor (IP receptor) signaling pathway in cerebral microvessels plays an important role in the metabolism of amyloid precursor protein (APP). In human brain microvascular endothelial cells activation of IP receptor with the stable a...

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Detalles Bibliográficos
Publicado en:J Cereb Blood Flow Metab
Autores principales: He, Tongrong, Santhanam, Anantha Vijay R, Lu, Tong, d'Uscio, Livius V, Katusic, Zvonimir S
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363732/
https://ncbi.nlm.nih.gov/pubmed/26661245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X15618977
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