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PPARδ agonist GW501516 prevents uncoupling of endothelial nitric oxide synthase in cerebral microvessels of hph-1 mice

Peroxisome proliferator-activated receptor delta (PPARδ) is ubiquitously expressed in the vasculature, including cerebral circulation. The role of PPARδ in metabolism of tetrahydrobiopterin (BH(4)) has not been studied in the cerebral microvasculature. In the present study, the effects of PPARδ agon...

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Bibliografiske detaljer
Main Authors: Santhanam, Anantha Vijay R., d’Uscio, Livius V., He, Tongrong, Katusic, Zvonimir S.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474319/
https://ncbi.nlm.nih.gov/pubmed/22982594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.09.012
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