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PPARδ agonist GW501516 prevents uncoupling of endothelial nitric oxide synthase in cerebral microvessels of hph-1 mice

Peroxisome proliferator-activated receptor delta (PPARδ) is ubiquitously expressed in the vasculature, including cerebral circulation. The role of PPARδ in metabolism of tetrahydrobiopterin (BH(4)) has not been studied in the cerebral microvasculature. In the present study, the effects of PPARδ agon...

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Main Authors: Santhanam, Anantha Vijay R., d’Uscio, Livius V., He, Tongrong, Katusic, Zvonimir S.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474319/
https://ncbi.nlm.nih.gov/pubmed/22982594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.09.012
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