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Uncoupling of endothelial nitric oxide synthase in cerebral vasculature of Tg2576 mice

In the present study we tested the hypothesis that reduced bioavailability of tetrahydrobiopterin (BH(4)) is a major mechanism responsible for pathogenesis of endothelial dysfunction in cerebral microvessels of transgenic mice expressing the Swedish double mutation of human amyloid precursor protein...

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Bibliografische gegevens
Gepubliceerd in:J Neurochem
Hoofdauteurs: Santhanam, Anantha Vijay R., d’Uscio, Livius V., He, Tongrong, Das, Pritam, Younkin, Steven G., Katusic, Zvonimir S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627976/
https://ncbi.nlm.nih.gov/pubmed/26111938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13205
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