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Activation of PPARδ prevents endothelial dysfunction induced by overexpression of amyloid-β precursor protein

AIMS: Existing evidence suggests that amyloid-β precursor protein (APP) causes endothelial dysfunction and contributes to pathogenesis of atherosclerosis. In the present study, experiments were designed to: (1) determine the mechanisms underlying endothelial dysfunction and (2) define the effects of...

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Detalhes bibliográficos
Main Authors: d'Uscio, Livius V., Das, Pritam, Santhanam, Anantha V.R., He, Tongrong, Younkin, Steven G., Katusic, Zvonimir S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500044/
https://ncbi.nlm.nih.gov/pubmed/22886847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs266
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