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Impairment of amyloid precursor protein alpha-processing in cerebral microvessels of type 1 diabetic mice
The mechanisms underlying dysfunction of cerebral microvasculature induced by type 1 diabetes (T1D) are not fully understood. We hypothesized that in cerebral microvascular endothelium, α-processing of amyloid precursor protein (APP) is impaired by T1D. In cerebral microvessels derived from streptoz...
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| Publié dans: | J Cereb Blood Flow Metab |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
SAGE Publications
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6547183/ https://ncbi.nlm.nih.gov/pubmed/29251519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17746981 |
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