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Impairment of amyloid precursor protein alpha-processing in cerebral microvessels of type 1 diabetic mice

The mechanisms underlying dysfunction of cerebral microvasculature induced by type 1 diabetes (T1D) are not fully understood. We hypothesized that in cerebral microvascular endothelium, α-processing of amyloid precursor protein (APP) is impaired by T1D. In cerebral microvessels derived from streptoz...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: He, Tongrong, Sun, Ruohan, Santhanam, Anantha VR, d'Uscio, Livius V, Lu, Tong, Katusic, Zvonimir S
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547183/
https://ncbi.nlm.nih.gov/pubmed/29251519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X17746981
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