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Expression and Processing of Amyloid Precursor Protein in Vascular Endothelium
Amyloid precursor protein (APP) is evolutionary conserved protein expressed in endothelial cells of cerebral and peripheral arteries. In this review, we discuss mechanisms responsible for expression and proteolytic cleavage of APP in endothelial cells. We focus on physiological and pathological impl...
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Publicado no: | Physiology (Bethesda) |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5338593/ https://ncbi.nlm.nih.gov/pubmed/27927802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00021.2016 |
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