Expression and Processing of Amyloid Precursor Protein in Vascular Endothelium

Amyloid precursor protein (APP) is evolutionary conserved protein expressed in endothelial cells of cerebral and peripheral arteries. In this review, we discuss mechanisms responsible for expression and proteolytic cleavage of APP in endothelial cells. We focus on physiological and pathological impl...

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Bibliographic Details
Published in:Physiology (Bethesda)
Main Authors: d'Uscio, Livius V., He, Tongrong, Katusic, Zvonimir S.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2016
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Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5338593/
https://ncbi.nlm.nih.gov/pubmed/27927802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiol.00021.2016
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