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Activation of PPARδ prevents endothelial dysfunction induced by overexpression of amyloid-β precursor protein
AIMS: Existing evidence suggests that amyloid-β precursor protein (APP) causes endothelial dysfunction and contributes to pathogenesis of atherosclerosis. In the present study, experiments were designed to: (1) determine the mechanisms underlying endothelial dysfunction and (2) define the effects of...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3500044/ https://ncbi.nlm.nih.gov/pubmed/22886847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs266 |
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