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Erythropoietin increases bioavailability of tetrahydrobiopterin and protects cerebral microvasculature against oxidative stress induced by eNOS uncoupling

The present study was designed to determine whether treatment with erythropoietin (EPO) could protect cerebral microvasculature against the pathological consequences of endothelial nitric oxide synthase (eNOS) uncoupling. Wild-type and GTP cyclohydrolase I (GTPCH-I)-deficient hph1 mice were administ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurochem
Hauptverfasser: Santhanam, Anantha Vijay R, d’Uscio, Livius V., Katusic, Zvonimir S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222993/
https://ncbi.nlm.nih.gov/pubmed/25041251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12824
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