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Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I

Tetrahydrobiopterin (BH(4)) is a critical determinant of nitric oxide (NO) production by nitric oxide synthase (NOS) in the vascular endothelium and its biosynthesis is regulated by the enzymatic activity of GTP-cyclohydrolase I (GTPCH I). The present study was designed to determine the effects of e...

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Bibliografiske detaljer
Udgivet i:Brain Res
Main Authors: Santhanam, Anantha Vijay R., d’Uscio, Livius V., Katusic, Zvonimir S.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637228/
https://ncbi.nlm.nih.gov/pubmed/26343845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2015.08.034
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