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Differential effects of eNOS uncoupling on conduit and small arteries in GTP-cyclohydrolase I-deficient hph-1 mice

In the present study, we used the hph-1 mouse, which displays GTP-cyclohydrolase I (GTPCH I) deficiency, to test the hypothesis that loss of tetrahydrobiopterin (BH(4)) in conduit and small arteries activates compensatory mechanisms designed to protect vascular wall from oxidative stress induced by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: d'Uscio, Livius V., Smith, Leslie A., Katusic, Zvonimir S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233811/
https://ncbi.nlm.nih.gov/pubmed/21963838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00588.2011
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