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Erythropoietin prevents endothelial dysfunction in GTP-cyclohydrolase I-deficient hph1 mice

In the present study, we used the mutant hph-1 mouse model, that has deficiency in GTP-cyclohydrolase I (GTPCH I) activity, to test the hypothesis that erythropoietin (EPO) protects aortic wall from oxidative stress induced by uncoupling of endothelial nitric oxide synthase (eNOS). Both GTPCH I acti...

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Bibliografiska uppgifter
I publikationen:J Cardiovasc Pharmacol
Huvudupphovsmän: d'Uscio, Livius V., Santhanam, Anantha V.R., Katusic, Zvonimir S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261745/
https://ncbi.nlm.nih.gov/pubmed/25490417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000145
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