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Erythropoietin increases bioavailability of tetrahydrobiopterin and protects cerebral microvasculature against oxidative stress induced by eNOS uncoupling

The present study was designed to determine whether treatment with erythropoietin (EPO) could protect cerebral microvasculature against the pathological consequences of endothelial nitric oxide synthase (eNOS) uncoupling. Wild-type and GTP cyclohydrolase I (GTPCH-I)-deficient hph1 mice were administ...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Santhanam, Anantha Vijay R, d’Uscio, Livius V., Katusic, Zvonimir S
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222993/
https://ncbi.nlm.nih.gov/pubmed/25041251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12824
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