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Pseudouridines have context-dependent mutation and stop rates in high-throughput sequencing
The abundant RNA modification pseudouridine (Ψ) has been mapped transcriptome-wide by chemically modifying pseudouridines with carbodiimide and detecting the resulting reverse transcription stops in high-throughput sequencing. However, these methods have limited sensitivity and specificity, in part...
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| Publicado no: | RNA Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6161689/ https://ncbi.nlm.nih.gov/pubmed/29683381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1462654 |
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