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Determination of tRNA aminoacylation levels by high-throughput sequencing

Transfer RNA (tRNA) decodes mRNA codons when aminoacylated (charged) with an amino acid at its 3′ end. Charged tRNAs turn over rapidly in cells, and variations in charged tRNA fractions are known to be a useful parameter in cellular responses to stress. tRNA charging fractions can be measured for in...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Evans, Molly E., Clark, Wesley C., Zheng, Guanqun, Pan, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737633/
https://ncbi.nlm.nih.gov/pubmed/28586482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx514
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