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Determination of tRNA aminoacylation levels by high-throughput sequencing
Transfer RNA (tRNA) decodes mRNA codons when aminoacylated (charged) with an amino acid at its 3′ end. Charged tRNAs turn over rapidly in cells, and variations in charged tRNA fractions are known to be a useful parameter in cellular responses to stress. tRNA charging fractions can be measured for in...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737633/ https://ncbi.nlm.nih.gov/pubmed/28586482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx514 |
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