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tRNA base methylation identification and quantification via high-throughput sequencing

Eukaryotic transfer RNAs contain on average 14 modifications. Investigations of their biological functions require the determination of the modification sites and the dynamic variations of the modification fraction. Base methylation represents a major class of tRNA modification. Although many approa...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Clark, Wesley C., Evans, Molly E., Dominissini, Dan, Zheng, Guanqun, Pan, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066629/
https://ncbi.nlm.nih.gov/pubmed/27613580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.056531.116
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