tRNA base methylation identification and quantification via high-throughput sequencing

Eukaryotic transfer RNAs contain on average 14 modifications. Investigations of their biological functions require the determination of the modification sites and the dynamic variations of the modification fraction. Base methylation represents a major class of tRNA modification. Although many approa...

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Bibliografiske detaljer
Udgivet i:RNA
Main Authors: Clark, Wesley C., Evans, Molly E., Dominissini, Dan, Zheng, Guanqun, Pan, Tao
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2016
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Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066629/
https://ncbi.nlm.nih.gov/pubmed/27613580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.056531.116
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