Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium

Ferroptosis is a death program executed via selective oxidation of arachidonic acid–phosphatidylethanolamines (AA-PE) by 15-lipoxygenases. In mammalian cells and tissues, ferroptosis has been pathogenically associated with brain, kidney, and liver injury/diseases. We discovered that a prokaryotic ba...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Dar, Haider H., Tyurina, Yulia Y., Mikulska-Ruminska, Karolina, Shrivastava, Indira, Ting, Hsiu-Chi, Tyurin, Vladimir A., Krieger, James, St. Croix, Claudette M., Watkins, Simon, Bayir, Erkan, Mao, Gaowei, Armbruster, Catherine R., Kapralov, Alexandr, Wang, Hong, Parsek, Matthew R., Anthonymuthu, Tamil S., Ogunsola, Abiola F., Flitter, Becca A., Freedman, Cody J., Gaston, Jordan R., Holman, Theodore R., Pilewski, Joseph M., Greenberger, Joel S., Mallampalli, Rama K., Doi, Yohei, Lee, Janet S., Bahar, Ivet, Bomberger, Jennifer M., Bayır, Hülya, Kagan, Valerian E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159971/
https://ncbi.nlm.nih.gov/pubmed/30198910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99490
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