Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium

Ferroptosis is a death program executed via selective oxidation of arachidonic acid–phosphatidylethanolamines (AA-PE) by 15-lipoxygenases. In mammalian cells and tissues, ferroptosis has been pathogenically associated with brain, kidney, and liver injury/diseases. We discovered that a prokaryotic ba...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Dar, Haider H., Tyurina, Yulia Y., Mikulska-Ruminska, Karolina, Shrivastava, Indira, Ting, Hsiu-Chi, Tyurin, Vladimir A., Krieger, James, St. Croix, Claudette M., Watkins, Simon, Bayir, Erkan, Mao, Gaowei, Armbruster, Catherine R., Kapralov, Alexandr, Wang, Hong, Parsek, Matthew R., Anthonymuthu, Tamil S., Ogunsola, Abiola F., Flitter, Becca A., Freedman, Cody J., Gaston, Jordan R., Holman, Theodore R., Pilewski, Joseph M., Greenberger, Joel S., Mallampalli, Rama K., Doi, Yohei, Lee, Janet S., Bahar, Ivet, Bomberger, Jennifer M., Bayır, Hülya, Kagan, Valerian E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159971/
https://ncbi.nlm.nih.gov/pubmed/30198910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99490
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