Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium

Ferroptosis is a death program executed via selective oxidation of arachidonic acid–phosphatidylethanolamines (AA-PE) by 15-lipoxygenases. In mammalian cells and tissues, ferroptosis has been pathogenically associated with brain, kidney, and liver injury/diseases. We discovered that a prokaryotic ba...

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書誌詳細
出版年:J Clin Invest
主要な著者: Dar, Haider H., Tyurina, Yulia Y., Mikulska-Ruminska, Karolina, Shrivastava, Indira, Ting, Hsiu-Chi, Tyurin, Vladimir A., Krieger, James, St. Croix, Claudette M., Watkins, Simon, Bayir, Erkan, Mao, Gaowei, Armbruster, Catherine R., Kapralov, Alexandr, Wang, Hong, Parsek, Matthew R., Anthonymuthu, Tamil S., Ogunsola, Abiola F., Flitter, Becca A., Freedman, Cody J., Gaston, Jordan R., Holman, Theodore R., Pilewski, Joseph M., Greenberger, Joel S., Mallampalli, Rama K., Doi, Yohei, Lee, Janet S., Bahar, Ivet, Bomberger, Jennifer M., Bayır, Hülya, Kagan, Valerian E.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2018
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159971/
https://ncbi.nlm.nih.gov/pubmed/30198910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99490
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