Phylogenetic approach to recover integration dates of latent HIV sequences within-host

Given that HIV evolution and latent reservoir establishment occur continually within-host, and that latently infected cells can persist long-term, the HIV reservoir should comprise a genetically heterogeneous archive recapitulating within-host HIV evolution. However, this has yet to be conclusively...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Jones, Bradley R., Kinloch, Natalie N., Horacsek, Joshua, Ganase, Bruce, Harris, Marianne, Harrigan, P. Richard, Jones, R. Brad, Brockman, Mark A., Joy, Jeffrey B., Poon, Art F. Y., Brumme, Zabrina L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156657/
https://ncbi.nlm.nih.gov/pubmed/30185556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802028115
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