Phylogenetic approach to recover integration dates of latent HIV sequences within-host

Given that HIV evolution and latent reservoir establishment occur continually within-host, and that latently infected cells can persist long-term, the HIV reservoir should comprise a genetically heterogeneous archive recapitulating within-host HIV evolution. However, this has yet to be conclusively...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Jones, Bradley R., Kinloch, Natalie N., Horacsek, Joshua, Ganase, Bruce, Harris, Marianne, Harrigan, P. Richard, Jones, R. Brad, Brockman, Mark A., Joy, Jeffrey B., Poon, Art F. Y., Brumme, Zabrina L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156657/
https://ncbi.nlm.nih.gov/pubmed/30185556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802028115
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