Phylogenetic approach to recover integration dates of latent HIV sequences within-host

Given that HIV evolution and latent reservoir establishment occur continually within-host, and that latently infected cells can persist long-term, the HIV reservoir should comprise a genetically heterogeneous archive recapitulating within-host HIV evolution. However, this has yet to be conclusively...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Jones, Bradley R., Kinloch, Natalie N., Horacsek, Joshua, Ganase, Bruce, Harris, Marianne, Harrigan, P. Richard, Jones, R. Brad, Brockman, Mark A., Joy, Jeffrey B., Poon, Art F. Y., Brumme, Zabrina L.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156657/
https://ncbi.nlm.nih.gov/pubmed/30185556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802028115
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