An Evaluation of Phylogenetic Methods for Reconstructing Transmitted HIV Variants using Longitudinal Clonal HIV Sequence Data

A population of human immunodeficiency virus (HIV) within a host often descends from a single transmitted/founder virus. The high mutation rate of HIV, coupled with long delays between infection and diagnosis, make isolating and characterizing this strain a challenge. In theory, ancestral reconstruc...

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Detalhes bibliográficos
Main Authors: McCloskey, Rosemary M., Liang, Richard H., Harrigan, P. Richard, Brumme, Zabrina L., Poon, Art F. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093844/
https://ncbi.nlm.nih.gov/pubmed/24648453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00483-14
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