Inactivation of PRIM1 Function Sensitizes Cancer Cells to ATR and CHK1 Inhibitors()

The phosphoinositide 3-kinase–related kinase ATR is a central regulator of the DNA damage response. Its chemical inhibition eliminates subsets of cancer cells in various tumor types. This effect is caused at least partly by the synthetically lethal relationship between ATR and certain DNA repair gen...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Job, Albert, Schmitt, Lisa-Maria, von Wenserski, Lisa, Lankat-Buttgereit, Brigitte, Gress, Thomas M., Buchholz, Malte, Gallmeier, Eike
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
Assuntos:
Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154763/
https://ncbi.nlm.nih.gov/pubmed/30257222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.08.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados