Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy

Flavokawain B (FKB), a natural kava chalcone, displays potent antitumor activity in various types of cancer. The mechanism of action, however, remains unclear. Here, we evaluated the efficacy of FKB in the treatment of human glioblastoma multiforme (GBM) as well as the molecular basis for its inhibi...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Wang, Jiwei, Qi, Qichao, Zhou, Wenjing, Feng, Zichao, Huang, Bin, Chen, Anjing, Zhang, Di, Li, Wenjie, Zhang, Qing, Jiang, Zheng, Bjerkvig, Rolf, Prestegarden, Lars, Thorsen, Frits, Wang, Xinyu, Li, Xingang, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper - Translational
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152528/
https://ncbi.nlm.nih.gov/pubmed/30025493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1501133
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