Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway

There is an urgent need for new therapeutic strategies for patients with glioblastoma multiforme (GBM). Previous studies have shown that berberine (BBR), a natural plant alkaloid, has potent anti-tumor activity. However, the mechanisms leading to cancer cell death have not been clearly elucidated. I...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Wang, Jiwei, Qi, Qichao, Feng, Zichao, Zhang, Xin, Huang, Bin, Chen, Anjing, Prestegarden, Lars, Li, Xingang, Wang, Jian
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341849/
https://ncbi.nlm.nih.gov/pubmed/27557493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11396
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