Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy

Flavokawain B (FKB), a natural kava chalcone, displays potent antitumor activity in various types of cancer. The mechanism of action, however, remains unclear. Here, we evaluated the efficacy of FKB in the treatment of human glioblastoma multiforme (GBM) as well as the molecular basis for its inhibi...

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Dades bibliogràfiques
Publicat a:Autophagy
Autors principals: Wang, Jiwei, Qi, Qichao, Zhou, Wenjing, Feng, Zichao, Huang, Bin, Chen, Anjing, Zhang, Di, Li, Wenjie, Zhang, Qing, Jiang, Zheng, Bjerkvig, Rolf, Prestegarden, Lars, Thorsen, Frits, Wang, Xinyu, Li, Xingang, Wang, Jian
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
Matèries:
Research Paper - Translational
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152528/
https://ncbi.nlm.nih.gov/pubmed/30025493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1501133
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