Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy

Flavokawain B (FKB), a natural kava chalcone, displays potent antitumor activity in various types of cancer. The mechanism of action, however, remains unclear. Here, we evaluated the efficacy of FKB in the treatment of human glioblastoma multiforme (GBM) as well as the molecular basis for its inhibi...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Wang, Jiwei, Qi, Qichao, Zhou, Wenjing, Feng, Zichao, Huang, Bin, Chen, Anjing, Zhang, Di, Li, Wenjie, Zhang, Qing, Jiang, Zheng, Bjerkvig, Rolf, Prestegarden, Lars, Thorsen, Frits, Wang, Xinyu, Li, Xingang, Wang, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Research Paper - Translational
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152528/
https://ncbi.nlm.nih.gov/pubmed/30025493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1501133
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