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AMPK lifts the PRC2-implemented gene repression

The crosstalk between cellular energy status and epigenetic modifications remains largely elusive. We recently uncovered that upon energy restriction, AMP-activated protein kinase (AMPK) phosphorylates enhancer of zeste homolog 2 (EZH2), which disrupts the integrity of the polycomb repressive comple...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Han, Tao, Yin, Qing, Wan, Lixin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149850/
https://ncbi.nlm.nih.gov/pubmed/30250895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1441632
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