PRC2 represses transcribed genes on the imprinted inactive X chromosome in mice

BACKGROUND: Polycomb repressive complex 2 (PRC2) catalyzes histone H3K27me3, which marks many transcriptionally silent genes throughout the mammalian genome. Although H3K27me3 is associated with silenced gene expression broadly, it remains unclear why some but not other PRC2 target genes require PRC...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genome Biol
Egile Nagusiak: Maclary, Emily, Hinten, Michael, Harris, Clair, Sethuraman, Shriya, Gayen, Srimonta, Kalantry, Sundeep
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2017
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5415793/
https://ncbi.nlm.nih.gov/pubmed/28468635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1211-5
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