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PRC2 represses transcribed genes on the imprinted inactive X chromosome in mice
BACKGROUND: Polycomb repressive complex 2 (PRC2) catalyzes histone H3K27me3, which marks many transcriptionally silent genes throughout the mammalian genome. Although H3K27me3 is associated with silenced gene expression broadly, it remains unclear why some but not other PRC2 target genes require PRC...
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| Publicado en: | Genome Biol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5415793/ https://ncbi.nlm.nih.gov/pubmed/28468635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1211-5 |
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