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Conversion of random X-inactivation to imprinted X-inactivation by maternal PRC2
Imprinted X-inactivation silences genes exclusively on the paternally-inherited X-chromosome and is a paradigm of transgenerational epigenetic inheritance in mammals. Here, we test the role of maternal vs. zygotic Polycomb repressive complex 2 (PRC2) protein EED in orchestrating imprinted X-inactiva...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541438/ https://ncbi.nlm.nih.gov/pubmed/30938678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44258 |
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