A primary role for the Tsix lncRNA in maintaining random X-chromosome inactivation

Differentiating pluripotent epiblast cells in eutherians undergo random X-inactivation, which equalizes X-linked gene expression between the sexes by silencing one of the two X-chromosomes in females. Tsix RNA is believed to orchestrate the initiation of X-inactivation, influencing the choice of whi...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Gayen, Srimonta, Maclary, Emily, Buttigieg, Emily, Hinten, Michael, Kalantry, Sundeep
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4449283/
https://ncbi.nlm.nih.gov/pubmed/25981039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.04.039
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