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A primary role for the Tsix lncRNA in maintaining random X-chromosome inactivation
Differentiating pluripotent epiblast cells in eutherians undergo random X-inactivation, which equalizes X-linked gene expression between the sexes by silencing one of the two X-chromosomes in females. Tsix RNA is believed to orchestrate the initiation of X-inactivation, influencing the choice of whi...
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| Publié dans: | Cell Rep |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4449283/ https://ncbi.nlm.nih.gov/pubmed/25981039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.04.039 |
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