PRC2 overexpression and PRC2-target gene repression relating to poorer prognosis in small cell lung cancer

Small cell lung cancer (SCLC) is a subtype of lung cancer with poor prognosis. Expression array analysis of 23 SCLC cases and 42 normal tissues revealed that EZH2 and other PRC2 members were highly expressed in SCLC. ChIP-seq for H3K27me3 suggested that genes with H3K27me3(+) in SCLC were extended n...

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Main Authors: Sato, Teruyuki, Kaneda, Atsushi, Tsuji, Shingo, Isagawa, Takayuki, Yamamoto, Shogo, Fujita, Takanori, Yamanaka, Ryota, Tanaka, Yukiko, Nukiwa, Toshihiro, Marquez, Victor E., Ishikawa, Yuichi, Ichinose, Masakazu, Aburatani, Hiroyuki
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665955/
https://ncbi.nlm.nih.gov/pubmed/23714854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01911
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