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DNA Methylation Profiling of Embryonic Stem Cell Differentiation into the Three Germ Layers

Embryogenesis is tightly regulated by multiple levels of epigenetic regulation such as DNA methylation, histone modification, and chromatin remodeling. DNA methylation patterns are erased in primordial germ cells and in the interval immediately following fertilization. Subsequent developmental repro...

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Detalhes bibliográficos
Main Authors: Isagawa, Takayuki, Nagae, Genta, Shiraki, Nobuaki, Fujita, Takanori, Sato, Noriko, Ishikawa, Shumpei, Kume, Shoen, Aburatani, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189249/
https://ncbi.nlm.nih.gov/pubmed/22016810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026052
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