Histone modification alteration coordinated with acquisition of promoter DNA methylation during Epstein-Barr virus infection

Aberrant DNA hypermethylation is a major epigenetic mechanism to inactivate tumor suppressor genes in cancer. Epstein-Barr virus positive gastric cancer is the most frequently hypermethylated tumor among human malignancies. Herein, we performed comprehensive analysis of epigenomic alteration during...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Funata, Sayaka, Matsusaka, Keisuke, Yamanaka, Ryota, Yamamoto, Shogo, Okabe, Atsushi, Fukuyo, Masaki, Aburatani, Hiroyuki, Fukayama, Masashi, Kaneda, Atsushi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589657/
https://ncbi.nlm.nih.gov/pubmed/28903418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19423
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